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Our wheat germ cell-free expression system was used in a study to clarify the side effects of thalidomide. | CellFree Sciences

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Our wheat germ cell-free expression system was used in a study to clarify the side effects of thalidomide.

Category: Announcements Created: Tuesday, 06 October 2020

Furihata, H., Yamanaka, S., Honda, T. et al. published in Nature Communications the results from a jointed project conducted by researchers at the University of Tokyo, Nagoya Institute of Technology, and our strategic partner the Proteo-Science Center at Ehime University using structural biology for determining the mechanisms behind side effects of immunomodulatory drugs like Thalidomide and its metabolite 5-hydroxythalidomide.

 

Thalidomide is used as an effective anti-cancer drug for treatment of multiple myeloma, although it exhibits side effects that cause developmental disorders in children during pregnancy. It is hoped that the results will help in the future to design better immunomodulatory drugs that mitigate the side effects.

 

This publication can be freely accessed: here.

 

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